欧盟就重新评估专利蓝V用作食品添加剂发布意见
日期:2017-10-07 / 人气: / 来源:本站
食品伙伴网讯 据欧盟食品安全局(EFSA)消息,3月1日欧盟食品安全局专家组就重新评估专利蓝V(Patent Blue V ,E 131)用作食品添加剂发布了意见。
欧盟专家组认为,按照专利蓝V最大允许使用限量来看,学步幼儿与儿童的ADI值在5mg/kg bw/day之上。按照目前报告的最大使用限量来看,所有年龄群体的ADI值在5mg/kg bw/day以下。
部分原文报道如下:
The Panel on Food Additives and Nutrient Sources added to Food provides a scientific opinion re-evaluating the safety of Patent Blue V (E 131)。 Patent Blue V (E 131) is a triarylmethane dye permitted for use as a food additive in the EU, that has been previously evaluated by JECFA in 1970 and 1975 and the EU SCF in 1983; JECFA established a Temporary Acceptable Daily Intake (ADI) of 0-1 mg/kg bw/day in 1970, but withdrew it in 1975. Until now JECFA has not allocated an ADI to Patent Blue V (E 131)。 The SCF established an ADI of 0-15 mg/kg bw/day.
The Panel was not provided with a newly submitted dossier and based its evaluation on previous evaluations, additional literature that became available since then and the data available following a public call for data. The Panel concluded that the present dataset provides a rationale for a re-definition of the ADI. Using the NOAEL of 500 mg/kg bw/day derived from a chronic toxicity study in mice and applying an uncertainty factor of 100 to this NOAEL, the Panel establishes an ADI of 5 mg/kg bw/day.
The Panel noted that at the maximum permitted levels of use of Patent Blue V (E 131),, exposure estimates for high consumers are above the ADI of 5 mg/kg bw/day in toddlers and children. At the maximum reported use levels of Patent Blue V (E 131), exposure estimates are below the ADI of 5 mg/kg bw/day for all groups of the population.
原文链接:<>
作者:中立达资产评估
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